Dr. Anthony Fauci set a new 'standard of care' for coronavirus treatment
By MYBRANDBOOK
In a significant development to control the pandemic COVID-19, gifted by Wuhan,China to the whole world, White House health advisor Dr. Anthony Fauci said that data from a coronavirus drug trial testing Gilead Sciences’ antiviral drug remdesivir showed “quite good news” and sets a new standard of care for Covid-19 patients.
Dr. Fauci said he was told data from the trial showed a “clear-cut positive effect in diminishing time to recover.”
Dr. Fauci said the median time of recovery for patients taking the drug was 11 days, compared with 15 days in the placebo group. He said the mortality benefit of remdesivir “has not yet reached statistical significance.”
The results suggested a survival benefit, with a mortality rate of 8% for the group receiving remdesivir versus 11.6% for the placebo group, according to a statement from the National Institutes of Health released later Wednesday.
“This will be the standard of care,” Fauci, director of the National Institute of Allergy and Infectious Diseases, added. “When you know a drug works, you have to let people in the placebo group know so they can take it.”
“What it has proven is a drug can block this virus,” he said.
U.S. health officials are expected to release the full results of a drug trial conducted by the National Institute of Allergy and Infectious Diseases later Wednesday. Gilead Sciences announced earlier in the day that the study had met its primary endpoint but did not provide further details.
The result is showing at least 50% of the patients treated with a five-day dosage of remdesivir improved. The clinical trial involved 397 patients with severe cases of Covid-19. The severe study is “single-arm,” meaning it did not evaluate the drug against a control group of patients who didn’t receive the drug.
The Food and Drug Administration, in the meantime, has been in “sustained and ongoing” discussions with Gilead to make remdesivir available to Covid-19 patients “as quickly as possible, as appropriate,” said FDA senior advisor Michael Felberbaum. Shares of Gilead were up by more than 5% at close and by more than 2% in extended hours trading.
The U.S. health officials say producing a vaccine to prevent the disease will take at least 12 to 18 months, making finding an effective drug treatment soon even more crucial.
President Donald Trump has touted Gilead’s remdesivir as a potential treatment for the virus. A number of studies are testing the drug to see if it’s effective in stopping the coronavirus from replicating, but it is not yet a proven treatment.
Remdesivir has shown some promise in treating SARS and MERS, which are also caused by coronaviruses. Some health authorities in the U.S., China and other parts of the world have been using remdesivir, which was tested as a possible treatment for the Ebola outbreak, in hopes that the drug can reduce the duration of Covid-19 in patients.
Dr. Fauci warned that the United States “could be in for a bad fall” if researchers don’t find an effective treatment to fight the coronavirus by then.
Covid-19 is “not going to disappear from the planet,” he said, adding infectious disease experts are learning about how the virus behaves by watching emerging outbreaks in other regions such as southern Africa that are starting to enter their colder seasons.
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